Vascular complications of hyaluronic acid fillers and the role of hyaluronidase in management.

  title={Vascular complications of hyaluronic acid fillers and the role of hyaluronidase in management.},
  author={Deok-Woo Kim and Eul-Sik Yoon and Yi-Hwa Ji and S Park and Byung-il Lee and Eun-Sang Dhong},
  journal={Journal of plastic, reconstructive & aesthetic surgery : JPRAS},
  volume={64 12},
Skin necrosis following the inadvertent arterial injection of hyaluronic acid (HA) is a serious complication. It is not clear whether or not subcutaneous injections of hyaluronidase decrease skin necrosis in HA-induced vascular complications. We had four cases of HA-induced vascular complications, two of which were treated with hyaluronidase the next day. All of the patients had skin necrosis and scarring. We performed an animal study with rabbit ears in which HA filler was injected into the… CONTINUE READING

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