Vascular cell adhesion molecule-1: a viable therapeutic target for atherosclerosis?

  title={Vascular cell adhesion molecule-1: a viable therapeutic target for atherosclerosis?},
  author={David J Preiss and Naveed 4 Sattar},
  journal={International journal of clinical practice},
  volume={61 4},
Atherosclerosis is now well recognised as a chronic inflammatory process which may ultimately lead to myocardial infarction, stroke and peripheral vascular disease. The role of inflammation in the pathogenesis of atherosclerosis has lead to interest in developing therapies that target vascular inflammation. Leucocytes play a key role during atherosclerotic plaque development. Activated vascular endothelium expresses vascular cell adhesion cell molecule-1 (VCAM-1), a member of the adhesion… CONTINUE READING
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