Vascular biology of eicosanoids and atherogenesis.

  title={Vascular biology of eicosanoids and atherogenesis.},
  author={Domenico Pratic{\`o} and J M Dogn{\'e}},
  journal={Expert review of cardiovascular therapy},
  volume={7 9},
Atherosclerosis is a chronic and progressive inflammatory vascular disease that is characterized by a complex interplay between some components of the bloodstream and the arterial wall. The lipid derivatives eicosanoids have been identified as important mediators that contribute to mechanisms of atherogenesis. Prostaglandins and thromboxane A2 are members of the eicosanoid family synthesized from arachidonic acid by the combined action of cyclooxygenases and prostaglandins and thromboxane A2… CONTINUE READING


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