Vascular and metabolic effects of treatment of combined hyperlipidemia: focus on statins and fibrates.

@article{Koh2008VascularAM,
  title={Vascular and metabolic effects of treatment of combined hyperlipidemia: focus on statins and fibrates.},
  author={Kwang Kon Koh and Michael J. Quon and Robert S Rosenson and Wook-Jin Chung and Seung Hwan Han},
  journal={International journal of cardiology},
  year={2008},
  volume={124 2},
  pages={
          149-59
        }
}
Combined hyperlipidemia results from overproduction of hepatically synthesized apolipoprotein B in very low-density lipoproteins in association with reduced lipoprotein lipase activity. Thus, this condition is typically characterized by concurrent elevations in total cholesterol and triglycerides with decreased high-density lipoprotein cholesterol. High levels of apolipoprotein B-containing lipoproteins, most prominently carried by low-density lipoprotein (LDL) particles, are an important risk… CONTINUE READING

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