Vascular adaptations to pregnancy in mice: effects on myogenic tone.

  title={Vascular adaptations to pregnancy in mice: effects on myogenic tone.},
  author={Sukrutha Veerareddy and Christy-Lynn M. Cooke and Philip N. Baker and Sandra T Davidge},
  journal={American journal of physiology. Heart and circulatory physiology},
  volume={283 6},
The mechanisms underlying vascular adaptations in pregnancy remain to be fully elucidated. One of the contributory mechanisms for reduced vascular tone may be a reduction of myogenic tone. Myogenic tone was assessed as the difference between internal diameter in the presence and absence of external calcium at different intramural pressure steps (60-100 mmHg). Myogenic responses were reduced in resistance-sized mesenteric and main uterine arteries in late pregnant compared with nonpregnant C57BL… CONTINUE READING
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