Vascular actions of C-type natriuretic peptide in isolated porcine coronary arteries and coronary vascular smooth muscle cells.

@article{Wei1994VascularAO,
  title={Vascular actions of C-type natriuretic peptide in isolated porcine coronary arteries and coronary vascular smooth muscle cells.},
  author={Chuncheng Wei and Shiling Hu and Virginia M Miller and John C Jr. Burnett},
  journal={Biochemical and biophysical research communications},
  year={1994},
  volume={205 1},
  pages={
          765-71
        }
}
C-type natriuretic (CNP) caused concentration-dependent relaxations in porcine coronary arteries with a maximal relaxation (10(-6)M) of 46%. Relaxations to CNP in isolated coronary arteries were significantly attenuated with potassium channel antagonists charybdotoxin (10(-7)M) and glibenclamide (10(-7)M). Membrane potential and K+ currents were measured in enzymatically dissociated smooth muscle cells from porcine coronary arteries with patch-clamp techniques in a whole-cell mode (n = 5). CNP… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 46 CITATIONS

Similar Papers

Loading similar papers…