Vascular Targeting of Nanocarriers: Perplexing Aspects of the Seemingly Straightforward Paradigm

Abstract

Targeted nanomedicine holds promise to find clinical use in many medical areas. Endothelial cells that line the luminal surface of blood vessels represent a key target for treatment of inflammation, ischemia, thrombosis, stroke, and other neurological, cardiovascular, pulmonary, and oncological conditions. In other cases, the endothelium is a barrier for… (More)
DOI: 10.1021/nn500136z

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