Vascular Ageing and Exercise: Focus on Cellular Reparative Processes

  title={Vascular Ageing and Exercise: Focus on Cellular Reparative Processes},
  author={Mark D Ross and Eva M Malone and Geraint D. Florida-James},
  booktitle={Oxidative medicine and cellular longevity},
Ageing is associated with an increased risk of developing noncommunicable diseases (NCDs), such as diabetes and cardiovascular disease (CVD). The increased risk can be attributable to increased prolonged exposure to oxidative stress. Often, CVD is preceded by endothelial dysfunction, which carries with it a proatherothrombotic phenotype. Endothelial senescence and reduced production and release of nitric oxide (NO) are associated with "vascular ageing" and are often accompanied by a reduced… CONTINUE READING
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