Vasa recta voltage-gated Na+ channel Nav1.3 is regulated by calmodulin.

@article{LeeKwon2007VasaRV,
  title={Vasa recta voltage-gated Na+ channel Nav1.3 is regulated by calmodulin.},
  author={Whaseon Lee‐Kwon and Jae Hwan Goo and Zhong Zhang and Erik P. Silldorff and Thomas L. Pallone},
  journal={American journal of physiology. Renal physiology},
  year={2007},
  volume={292 1},
  pages={
          F404-14
        }
}
Rat descending vasa recta (DVR) express a tetrodotoxin (TTX)-sensitive voltage-operated Na(+) (Na(V)) conductance. We examined expression of Na(V) isoforms in DVR and tested for regulation of Na(V) currents by calmodulin (CaM). RT-PCR in isolated permeabilized DVR using degenerate primers targeted to TTX-sensitive isoforms amplified a product whose sequence identified only Na(V)1.3. Immunoblot of outer medullary homogenate verified Na(V)1.3 expression, and fluorescent immunochemistry showed Na… 
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