Vasa-Like DEAD-Box RNA Helicases of Schistosoma mansoni

@inproceedings{Skinner2012VasaLikeDR,
  title={Vasa-Like DEAD-Box RNA Helicases of Schistosoma mansoni},
  author={Danielle Skinner and Gabriel Rinaldi and Sutas Suttiprapa and Victoria H Mann and Pablo Smircich and Alexis A. Cogswell and David L Williams and Paul J. Brindley},
  booktitle={PLoS neglected tropical diseases},
  year={2012}
}
Genome sequences are available for the human blood flukes, Schistosoma japonicum, S. mansoni and S. haematobium. Functional genomic approaches could aid in identifying the role and importance of these newly described schistosome genes. Transgenesis is established for functional genomics in model species, which can lead to gain- or loss-of-functions, facilitate vector-based RNA interference, and represents an effective forward genetics tool for insertional mutagenesis screens. Progress toward… CONTINUE READING

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