Various polar tripeptides as asymmetric organocatalyst in direct aldol reactions in aqueous media.

Abstract

A series of tripeptide organocatalysts containing a secondary amine group and two amino acids with polar side chain units were developed and evaluated in the direct asymmetric intermolecular aldol reaction of 4-nitrobenzaldehyde and cyclohexanone. The effectiveness of short polar peptides as asymmetric catalysts in aldol reactions to attain high yields of… (More)
DOI: 10.1002/chir.22205

Topics

  • Presentations referencing similar topics