Varicella zoster virus vaccines: effective, but concerns linger.

@article{Liesegang2009VaricellaZV,
  title={Varicella zoster virus vaccines: effective, but concerns linger.},
  author={Thomas J. Liesegang},
  journal={Canadian journal of ophthalmology. Journal canadien d'ophtalmologie},
  year={2009},
  volume={44 4},
  pages={
          379-84
        }
}
  • T. Liesegang
  • Published 1 August 2009
  • Medicine, Biology
  • Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
Both varicella and herpes zoster (HZ) can cause severe disease in certain age groups. The cell-mediated immune (CMI) response to the varicella zoster virus (VZV) is critical in preventing a recurrence of VZV. The varicella vaccine has markedly decreased the morbidity and mortality associated with varicella, but concerns linger about the cost and frequency of vaccine administration and the long-term effects on both adult varicella and HZ epidemiology in the individual and in the population… 
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27 Citations
Background Citations
9
Methods Citations
2

27 Citations

Zoster vaccine: current status and future prospects.
  • M. Oxman
  • Medicine, Biology
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2010
TLDR
Induction of VZV-specific cell-mediated immunity and not antibody should be used as a proxy for the clinical efficacy of new formulations and uses of zoster vaccine.
Importance of vaccination against herpes zoster
  • D. Evans
  • Medicine
    The Journal of the American Osteopathic Association
  • 2010
TLDR
In a recent population-based study in Olmsted County, Minn., researchers found that the incidence and rate of complications increased with age, with 68% of cases occurring in those aged 50 years and older.
Herpes Zoster Ophthalmicus.
VARICELLA-ZOSTER VIRUS ORF66 KINASE:REVEALING CRITICAL CELL-SPECIFIC ROLES OF THE KINASE AND ITS TARGETING OF THE NUCLEAR MATRIX PROTEIN, MATRIN 3
TLDR
It is found the ORF66 is critical for viral growth in primary corneal fibroblasts and thus established a model for further investigatation of cell-type dependent functions for ORF 66, and a novel ORf66 cellular target, the nuclear matrix protein, matrin 3 is described.
Herpes: Issues Under the Cold Sore
TLDR
In this review of herpes, there are three important points that need to be emphasized - herpes can be found in all organs throughout the human body and not just the dorsal root ganglion.
Shingles (herpes zoster).
TLDR
Even if older adults do not remember having chicken pox, they should still get vaccinated, and there is a vaccine, Zostavax®, available in your physician's office or at participating pharmacies.
T-cell epitope vaccine design by immunoinformatics
TLDR
Different sequence- and structure-based immunoinformatics methods are reviewed in the paper and the increased understanding of antigen recognition at molecular level has resulted in the development of rationally designed peptide vaccines.
Interaction between favipiravir and hydroxychloroquine and their combined drug assessment: in silico investigations
TLDR
The quantum theory of atoms in molecules was applied to explain the nature of the hydrogen bonds and confirm the higher stability of the combined drug, and the preliminary findings are promising for further investigations of more potent and selective antiviral drugs.
Therapeutic Replacements to Antibiotics
TLDR
This review article highlights various types of alternatives to antibiotics which are used for the treatment of bacterial infections.
Nanotechnologies Applied in Biomedical Vaccines
Vaccination, one of the most effective strategies to prevent infectious diseases, is the administration of antigenic materials to stimulate an individual’s immune system to develop adaptive immunity…
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