Varicella-zoster virus transcription in human trigeminal ganglia.

  title={Varicella-zoster virus transcription in human trigeminal ganglia.},
  author={Jeffery L. Meier and Ruth Holman and Kenneth D. Croen and John E Smialek and Stephen E. Straus},
  volume={193 1},
Our laboratory previously reported in situ hybridization analyses showing varicella-zoster virus (VZV)-specific RNA transcripts in latently infected human trigeminal ganglia. These transcripts were found exclusively in non-neuronal cells and emanated from at least three separate regions of the VZV genome, those encompassing restriction fragments BamHI-EY, EcoRI-B, and BamHI-J. Extending these in situ studies, we now report that VZV RNAs colinear with open reading frames (ORFs) 29 and 62 are… CONTINUE READING
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