Varicella-zoster virus ORF1 gene product is a tail-anchored membrane protein localized to plasma membrane and trans-Golgi network in infected cells.

@article{Koshizuka2008VaricellazosterVO,
  title={Varicella-zoster virus ORF1 gene product is a tail-anchored membrane protein localized to plasma membrane and trans-Golgi network in infected cells.},
  author={Tetsuo Koshizuka and Tomohiko Sadaoka and Hironori Yoshii and Koichi Yamanishi and Yasuko Mori},
  journal={Virology},
  year={2008},
  volume={377 2},
  pages={289-95}
}
Varicella-zoster virus (VZV) encodes five genes that do not have herpes simplex virus homologs. One of these genes, VZV open reading frame 1 (ORF1), encodes a membrane protein with a hydrophobic domain at its C-terminus that is predicted to be the transmembrane domain. However, the detailed characterization of ORF1 protein in infected cells has not been… CONTINUE READING