Varicella-zoster reactivation after allogeneic stem cell transplantation without routine prophylaxis--the incidence remains high.

One-year prophylaxis with acyclovir has been shown to effectively prevent varicella-zoster virus (VZV) reactivation after allogeneic hematopoietic stem cell transplantation (HSCT) in a cohort that underwent transplantation in the beginning of the 2000s. Transplantation procedures have since changed considerably and reduced-intensity conditioning (RIC) is… CONTINUE READING