Varicella-Zoster Virus Reactivation Is an Important Cause of Acute Peripheral Facial Paralysis in Children

@article{Furuta2005VaricellaZosterVR,
  title={Varicella-Zoster Virus Reactivation Is an Important Cause of Acute Peripheral Facial Paralysis in Children},
  author={Yasushi Furuta and Fumio Ohtani and Hiroshi Aizawa and Satoshi Fukuda and Hiroki Kawabata and Tomas Bergström},
  journal={The Pediatric Infectious Disease Journal},
  year={2005},
  volume={24},
  pages={97-101}
}
Background: Reactivation of herpes simplex virus type 1 is thought to be a major cause of adult idiopathic peripheral facial paralysis or Bell's palsy. However, few studies have examined the pathogenesis of this condition in children. Serologic assays and polymerase chain reaction (PCR) analysis of paired sera and saliva samples were used here to investigate the causes of acute peripheral facial paralysis in pediatric patients. Methods: A total of 30 children with acute peripheral facial… 
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89 Citations
Highly Influential Citations
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Background Citations
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Methods Citations
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Results Citations
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89 Citations

Reactivation of type 1 herpes simplex virus and varicella zoster virus in an immunosuppressed patient with acute peripheral facial weakness
Microbiologic Findings in Acute Facial Palsy in Children
TLDR
Cerebrospinal fluid sampling is recommended for all pediatric cases in endemic areas, as cause was highly plausible in 67% and probable in an additional 11% of cases, and microbes associated with facial palsy could frequently be confirmed.
The association of Varicella zoster virus reactivation with Bell's palsy in children.
The presence of herpes simplex-1 and varicella zoster viruses is not related with clinical outcome of Bell's Palsy.
Varicella-zoster virus infections of the central nervous system – Prognosis, diagnostics and treatment.
Neurologic Manifestations of Herpes Zoster
Are There Undiagnosed TBE-, Herpes- or Enteroviral Infections among Children Being Evaluated for Lyme Neuroborreliosis?
TLDR
The results suggest that undiagnosed herpes- or enteroviral infections are unlikely to explain CNS symptoms in children being evaluated for LNB, whereas missed TBE infections may occur.
Search for varicella zoster virus DNA in saliva of healthy individuals aged 20–59 years
TLDR
All neurological and ocular complications of varicella zoster virus (VZV) reactivation can occur without rash, and if VZV were readily detected in other tissue in patients with neurological disease without rash and found to correlate with tests listed above, more invasive tests such as lumbar puncture might be obviated.
Varicella-Zoster Virus Infections
TLDR
Clinicians must be aware that VZV reactivation produces multiple disorders of the central nervous system (CNS) and peripheral nervous system, often without rash, so rapid virologic verification and prompt treatment with antiviral agents can lead to complete recovery, even in patients with protracted disease.
Varicella zoster virus infection
TLDR
This Primer discusses the pathogenesis, diagnosis, treatment, and prevention of VZV infections, with an emphasis on the molecular events that regulate these diseases.
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References

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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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