Variations in the response of pituitary lactotrophs to oxytocin during the rat estrous cycle.

@article{Tabak2010VariationsIT,
  title={Variations in the response of pituitary lactotrophs to oxytocin during the rat estrous cycle.},
  author={Jo{\"e}l Tabak and Arturo E. Gonzalez-Iglesias and Natalia Toporikova and Richard Bertram and Marc E. Freeman},
  journal={Endocrinology},
  year={2010},
  volume={151 4},
  pages={
          1806-13
        }
}
Although removal of dopamine inhibition is established as a major factor in prolactin (PRL) release, a large body of evidence suggests that hypothalamic oxytocin (OT) may serve as a PRL-releasing hormone in the rat. PRL release is modulated by estradiol (E2), which rises between diestrus and proestrus of the estrous cycle, causing a PRL surge in the afternoon of proestrus. Given that E2 strongly modulates OT actions in both central and peripheral tissues, OT action on lactotrophs might also be… CONTINUE READING

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Modulation of Lactotroph Response to OT Endocrinology

  • AE Gonzalez-Iglesias, T Murano, S Li, M Tomic, SS TabakStojilkovic
  • Florida State University Ser Acq Unit/Lib Tech…
  • 2010
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