Variations in expression and release of botulinum neurotoxin in Clostridium botulinum type A strains.

@article{Rao2007VariationsIE,
  title={Variations in expression and release of botulinum neurotoxin in Clostridium botulinum type A strains.},
  author={Sphoorthy Rao and Renate L Starr and Melissa G Morris and W Lin},
  journal={Foodborne pathogens and disease},
  year={2007},
  volume={4 2},
  pages={201-7}
}
In this study, we characterized the production and release of botulinum neurotoxin during growth of two Clostridium botulinum strains, Hall A and NCTC2916, of distinct gene organizations. The intra- and extracellular fractions of the bacterial cells harvested at various stages of growth were analyzed for the neurotoxin. Both strains exhibited a temporal… CONTINUE READING