Variations in cell form and cytoskeleton in human breast carcinoma cells in vitro.

@article{Brinkley1980VariationsIC,
  title={Variations in cell form and cytoskeleton in human breast carcinoma cells in vitro.},
  author={Bill R. Brinkley and P T Beall and L J Wible and Myles L. Mace and David S. Turner and Relda Cailleau},
  journal={Cancer research},
  year={1980},
  volume={40 9},
  pages={3118-29}
}
Cell form and cytoskeletal organization were investigated in 13 human breast carcinoma cell lines in vitro. Using tubulin antibodies and indirect immunofluorescence to detect the arrangement of cytoplasmic microtubules, three distinct cell phenotypes were recognized: (a) cells with extensive arrays of microtubules (type 1); (b) cells which were diffusely stained with microtubules apparent only near the cell margins (type II intermediate); and (c) cells in which individual microtubules could not… CONTINUE READING

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