Variations in activin receptor, inhibin/activin subunit and follistatin mRNAs in human prostate tumour tissues

@article{Schaik2000VariationsIA,
  title={Variations in activin receptor, inhibin/activin subunit and follistatin mRNAs in human prostate tumour tissues},
  author={Ron van Schaik and Cristel DJ Wierikx and M A Timmerman and Monique H. Oomen and Wytske M. van Weerden and Theodorus H. van der Kwast and Gert Jan van Steenbrugge and Frank H. de Jong},
  journal={British Journal of Cancer},
  year={2000},
  volume={82},
  pages={112 - 117}
}
The possible role of activin in the regulation of malignant prostatic growth was studied using RNAase protection assays of activin receptors, inhibin/activin subunits and follistatin mRNAs in the human prostatic carcinoma cell lines LNCaP-FGC, -R and -LNO, in human prostatic carcinoma xenografts and in human prostatic tissue. Activin receptor types IA (ActRIA), IB (ActRIB), IIA (ActRIIA) and IIB (ActRIIB) mRNAs were generally expressed in prostate pithelial cells, with significantly lower… CONTINUE READING