Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts

@article{Lallemand1997VariationsIJ,
  title={Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts},
  author={Dominique Lallemand and Giannis Spyrou and M. Yaniv and Curt M Pfarr},
  journal={Oncogene},
  year={1997},
  volume={14},
  pages={819-830}
}
We have analysed the different Jun and Fos proteins as NIH3T3 fibroblasts pass from exponential growth to quiescence and during the first 24 h after their re-entry into the cell cycle following serum stimulation. We show that these proteins can be divided into 3 subgroups based on their pattern of expression. The first contains c-Jun, Jun-D and Fra-2 which are expressed at high level in cycling cells and are only mildly induced by serum. The second contains Jun-B, c-Fos, Fos-B and ΔFos-B whose… CONTINUE READING