Variations in Brain Volume and Growth in Young Children With Type 1 Diabetes

@inproceedings{Mazaika2016VariationsIB,
  title={Variations in Brain Volume and Growth in Young Children With Type 1 Diabetes},
  author={Paul K Mazaika and Stuart Weinzimer and Nelly Mauras and Bruce A. Buckingham and N. H. White and Eva Tsalikian and Tamara Hershey and Allison Cato and Tandy Aye and Larry A Fox and Darrell M. Wilson and Michael Jeremiah Tansey and William V Tamborlane and Daniel X Peng and Mira M. Raman and Matthew J. Marzelli and Allan L. Reiss},
  booktitle={Diabetes},
  year={2016}
}
Early-onset type 1 diabetes may affect the developing brain during a critical window of rapid brain maturation. Structural MRI was performed on 141 children with diabetes (4-10 years of age at study entry) and 69 age-matched control subjects at two time points spaced 18 months apart. For the children with diabetes, the mean (±SD) HbA1c level was 7.9 ± 0.9% (63 ± 9.8 mmol/mol) at both time points. Relative to control subjects, children with diabetes had significantly less growth of cortical gray… CONTINUE READING
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Persistence of abnormalities in white matter in children with type 1 diabetes

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