Variational expression of functionally different macrophage markers (27E10, 25F9, RM3/1) in normal gingiva and inflammatory periodontal disease

@article{Gmez1995VariationalEO,
  title={Variational expression of functionally different macrophage markers (27E10, 25F9, RM3/1) in normal gingiva and inflammatory periodontal disease},
  author={R Schlegel G{\'o}mez and Paul H. Langer and Matthias Pelka and P von den Driesch and Anne Christine Johannessen and Marcia Simon},
  journal={Journal of clinical periodontology},
  year={1995},
  volume={22 5},
  pages={
          341-6
        }
}
Keratinocytes and macrophages share under immunologically activated conditions several surface proteins. We investigated immunohistochemically with monoclonal antibodies and the APAAP technique the expression pattern of 27E10 antigen (inflammatory macrophages), 25F9 antigen (resident macrophages) and RM3/1 antigen (intermediate macrophages in healing tissue) in 29 specimen biopsies of different stages of gingivitis and periodontitis. Macrophages of each subtype exhibited a different… CONTINUE READING