Variation of the genetic expression pattern after exposure to estradiol-17beta and 4-nonylphenol in male zebrafish (Danio rerio).

@article{Ruggeri2008VariationOT,
  title={Variation of the genetic expression pattern after exposure to estradiol-17beta and 4-nonylphenol in male zebrafish (Danio rerio).},
  author={Barbara Ruggeri and Massimo Ubaldi and Anbarasu Lourdusamy and Laura Soverchia and Rachel Ciccocioppo and Gary Hardiman and Michael E. Baker and Francesco Palermo and Alberta Maria Polzonetti-Magni},
  journal={General and comparative endocrinology},
  year={2008},
  volume={158 1},
  pages={138-44}
}
There is much concern about the increasing presence in the environment of synthetic chemicals that are able to disrupt the endocrine system. Among these compounds, 4-nonylphenol (4-NP) is one of the most studied xenoestrogens, due to its widespread accumulation in water sediment and consequent presence in fatty acid of aquatic organisms. Here, we have used a zebrafish microarray representing 16,399 genes to study the effects of 4-NP and estradiol-17beta (E2) in adult male zebrafish in order to… CONTINUE READING

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