Variation of mitochondrial gene and the association with type 2 diabetes mellitus in a Chinese population.

@article{Tang2006VariationOM,
  title={Variation of mitochondrial gene and the association with type 2 diabetes mellitus in a Chinese population.},
  author={Dong-ling Tang and Xin Zhou and Xia Li and Lei Zhao and Fang Liu},
  journal={Diabetes research and clinical practice},
  year={2006},
  volume={73 1},
  pages={77-82}
}
Mitochondrial DNA (mtDNA) variants have been implicated in many diseases including diabetes mellitus. To explore whether these genetic variants contribute to the susceptibility for type 2 diabetes mellitus (T2DM) in a Chinese population, a total of 184 T2DM cases and 279 matched healthy controls were recruited. PCR restriction fragment length polymorphism (PCR-RFLP) analysis and DNA sequencing were used to determine the variants of mtDNA (including T16189C, G3316A, T3394C, A14693G, A3243G and… CONTINUE READING

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