Variation of apolipoprotein-B gene is associated with obesity, high blood cholesterol levels, and increased risk of coronary heart disease.

@article{RajputWilliams1988VariationOA,
  title={Variation of apolipoprotein-B gene is associated with obesity, high blood cholesterol levels, and increased risk of coronary heart disease.},
  author={J Rajput-Williams and Timothy J. Knott and Steven C. Wallis and Peter M. Sweetnam and J A Yarnell and Nancy A Cox and Graeme I. Bell and Norman E. Miller and James M Scott},
  journal={Lancet},
  year={1988},
  volume={2 8626-8627},
  pages={1442-6}
}
A random sample of 290 white men was examined for association between restriction fragment length polymorphism (RFLP) haplotypes (closely linked RFLPs on a single chromosome) of the apolipoprotein-B gene and serum levels of cholesterol, triglyceride, and high-density lipoprotein, obesity, smoking, alcohol consumption, and coronary heart disease. Haplotype or single RFLP frequencies differed significantly for obesity (p less than 0.005), serum cholesterol (p less than 0.005), and coronary heart… CONTINUE READING
27 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

Similar Papers

Loading similar papers…