Variation of DAT1 VNTR Alleles and Genotypes Among Old Ethnic Groups in Mesopotamia to the Oxus Region

  title={Variation of DAT1 VNTR Alleles and Genotypes Among Old Ethnic Groups in Mesopotamia to the Oxus Region},
  author={Mohammad Mehdi Banoei and Morteza Hashemzadeh Chaleshtori and Mohammad Hossein Sanati and Parvin Shariati and Massoud Houshmand and Tayebeh Majidizadeh and Niloofar Jahangir Soltani and Massoud Golalipour},
  booktitle={Human biology},
ABSTRACT Variation of a VNTR in the DAT1 gene in seven ethnic groups of the Middle East was used to infer the history and affinities of these groups. The populations consisted of Assyrian, Jewish, Zoroastrian, Armenian, Turkmen, and Arab peoples of Iran, Iraq, and Kuwait. Three hundred forty subjects from these seven ethnic groups were screened for DAT1. DAT1 VNTR genotyping showed 3, 6, 7, 8, 9, 10, 11, and 12 alleles in the samples. Analysis of these data revealed differentiation and… 



Diversity and relationship between Iranian ethnic groups: Human dopamine transporter gene (DAT1) VNTR genotyping

This study shows that the DAT1 distribution in Iran has a different pattern from those in other studies, which can contribute to an understanding of differentiation and diversity of Iranian ethnic groups.

Distribution of the 3' VNTR polymorphism in the human dopamine transporter gene in world populations.

The results demonstrated that the DAT1 VNTR polymorphism is useful in investigating population relationships, and that rare alleles at this locus may be particularly valuable in understanding the extent of genetic affinity between neighboring groups and in situations where admixture is suspected.

HLA alleles and haplotypes in the Turkish population: relatedness to Kurds, Armenians and other Mediterraneans.

It is concluded that this invasion had a relatively few invaders in comparison to the already settled populations, i.e. Anatolian Hittite and Hurrian groups (older than 2000 B.C.), which may have given rise to present-day Kurdish, Armenian and Turkish populations.

Population genetic relationships between Mediterranean populations determined by HLA allele distribution and a historic perspective.

HLA genomics shows that Greeks share an important part of their genetic pool with sub-Saharan Africans (Ethiopians and west Africans) also supported by Chr 7 Markers and Kurds and Armenians are genetically very close to Turks and other Middle East populations.

Jewish and Middle Eastern non-Jewish populations share a common pool of Y-chromosome biallelic haplotypes.

The hypothesis that the paternal gene pools of Jewish communities from Europe, North Africa, and the Middle East descended from a common Middle Eastern ancestral population is supported, and most Jewish communities have remained relatively isolated from neighboring non-Jewish communities during and after the Diaspora is suggested.

Distribution of HLA-A alleles in eight ethnic groups from Pakistan.

A phylogenetic tree based on DA distances for HLA-A allele frequencies separated the Pakistani populations from other world populations and also separated the only Dravidian speaking population of Pakistan, the Brahui, from the remaining Indo-European speaking ethnic groups of Pakistan.

HLA analysis of the Parsi (Zoroastrian) population in Pakistan.

Data analysis suggests that the Parsis of Pakistan and India descended from the same stock and may have the closest ancestry with Jewish and Italian populations.

Amplification of DAT1 (human dopamine transporter gene) 3' variable region in the Japanese population.

Amplification of the human dopamine transporter gene (DAT1) was performed by the polymerase chain reaction, and polymorphism of the VNTR locus was analyzed in a population sample of 176 randomly

Genetic polymorphism of the 3' VNTR region of the human dopaminergic function gene DAT1 (human dopamine transporter gene) in the Mongolian population.

The hypervariable region of the dopamine transporter gene (DAT1) was amplified from samples in the Mongolian population. This region includes a variable number of tandem repeats of a 40-bp core unit

Distribution of alleles of drd4 and dat1 genes of the dopaminergic system in the mixed chilean population

In a Chilean population sample, the frequency of DRD4 and DAT1 alleles was very similar to that of European populations, particularly among Europeans and Amerindians.