Variation in the size of the repeat region of the fibrinogen receptor (clumping factor) of Staphylococcus aureus strains.

@article{McDevitt1995VariationIT,
  title={Variation in the size of the repeat region of the fibrinogen receptor (clumping factor) of Staphylococcus aureus strains.},
  author={Damien McDevitt and T. J. Foster},
  journal={Microbiology},
  year={1995},
  volume={141 ( Pt 4)},
  pages={937-43}
}
The ability of Staphylococcus aureus to bind to fibrinogen and fibrin is believed to be an important factor in the initiation of foreign body and wound infections. Recently, the gene encoding the fibrinogen receptor (clumping factor, ClfA) of S. aureus strain Newman was cloned and sequenced. The ClfA protein possesses a highly unusual 308 residue dipeptide repeat region composed predominantly of Asp and Ser. Polymerase chain reaction analysis of seven different strains showed that the size of… CONTINUE READING

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