Variation in the ovarian reserve is linked to alterations in intrafollicular estradiol production and ovarian biomarkers of follicular differentiation and oocyte quality in cattle.

@article{Ireland2009VariationIT,
  title={Variation in the ovarian reserve is linked to alterations in intrafollicular estradiol production and ovarian biomarkers of follicular differentiation and oocyte quality in cattle.},
  author={James J. Ireland and Anna E. Zielak-Steciwko and Fermin Jimenez-Krassel and Joseph K. Folger and Anilkumar Bettegowda and Danielle Marie Scheetz and Siobhan Walsh and Francesca Mossa and Philip G. Knight and George Wesley Tyler Smith and Patrick Gerard Lonergan and Alexander C. O. Evans},
  journal={Biology of reproduction},
  year={2009},
  volume={80 5},
  pages={
          954-64
        }
}
The mechanisms whereby the high variation in numbers of morphologically healthy oocytes and follicles in ovaries (ovarian reserve) may have an impact onovarian function, oocyte quality, and fertility are poorly understood. The objective was to determine whether previously validated biomarkers for follicular differentiation and function, as well as oocyte quality differed between cattle with low versus a high antral follicle count (AFC). Ovaries were removed (n = 5 per group) near the beginning… CONTINUE READING

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