Variation in the internalization of differently sized nanoparticles induces different DNA-damaging effects on a macrophage cell line

@article{Zhang2011VariationIT,
  title={Variation in the internalization of differently sized nanoparticles induces different DNA-damaging effects on a macrophage cell line},
  author={Mingyi Zhang and Juan Jenny Li and Gengmei Xing and Rui He and Wei Li and Yan Song and Haili Guo},
  journal={Archives of Toxicology},
  year={2011},
  volume={85},
  pages={1575-1588}
}
Although researchers have expended considerable effort on studying the cytotoxicity of nanomaterials, it is possible that there has been insufficient attention paid to their genotoxic potential. Here, we describe a test model that we have developed to evaluate the DNA-damaging effects of negatively charged nanoparticles of different sizes. We compared the… CONTINUE READING