Variation in the inflammatory properties of basic calcium phosphate crystals according to crystal type.

@article{Prudhommeaux1996VariationIT,
  title={Variation in the inflammatory properties of basic calcium phosphate crystals according to crystal type.},
  author={F Prudhommeaux and Corinne Schiltz and Fr{\'e}d{\'e}ric Liot{\'e} and A Hina and Romuald Champy and Barbara Bucki and E Ortiz-Bravo and Alain Meunier and Christian Rey and Thomas Bardin},
  journal={Arthritis and rheumatism},
  year={1996},
  volume={39 8},
  pages={1319-26}
}
OBJECTIVE To determine the inflammatory potential of basic calcium phosphate (BCP) crystals, which have been identified in human joints. METHODS Hydroxyapatite, carbonate apatite, whitlockite, and octacalcium phosphate crystals were injected in rat air pouches. Volume and cellularity of the exudate were measured. Physicochemical properties of the injected BCP crystals were determined, and correlations with the magnitude of induced inflammatory responses were sought. RESULTS Significant… CONTINUE READING
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