Variation in susceptibility to benznidazole in isolates derived from Trypanosoma cruzi parental strains.

@article{Veloso2001VariationIS,
  title={Variation in susceptibility to benznidazole in isolates derived from Trypanosoma cruzi parental strains.},
  author={Vanja Maria Veloso and Claudia M. Carneiro and Max Jean de Ornelas Toledo and Marta Lana and Egler Chiari and Washington Luiz Tafuri and Maria Terezinha Bahia},
  journal={Memorias do Instituto Oswaldo Cruz},
  year={2001},
  volume={96 7},
  pages={1005-11}
}
In this work, the susceptibility to benznidazole of two parental Trypanosoma cruzi strains, Colombian and Berenice-78, was compared to isolates obtained from dogs infected with these strains for several years. In order to evaluate the susceptibility to benznidazole two groups of mice were infected with one of five distinct populations isolated from dogs as well as the two parental strains of T. cruzi. The first group was treated with benznidazole during the acute phase and the second remained… CONTINUE READING

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