Variation in positively selected major histocompatibility complex class I loci in rufous-collared sparrows (Zonotrichia capensis)

@article{Jones2014VariationIP,
  title={Variation in positively selected major histocompatibility complex class I loci in rufous-collared sparrows (Zonotrichia capensis)},
  author={Matthew R. L. Jones and Zachary A. Cheviron and Matthew D. Carling},
  journal={Immunogenetics},
  year={2014},
  volume={66},
  pages={693-704}
}
The major histocompatibility complex (MHC) is a highly variable family of genes involved in parasite recognition and the initiation of adaptive immune system responses. Variation in MHC loci is maintained primarily through parasite-mediated selection or disassortative mate choice. To characterize MHC diversity of rufous-collared sparrows (Zonotrichia capensis), an abundant South American passerine, we examined allelic and nucleotide variation in MHC class I exon 3 using pyrosequencing. Exon 3… CONTINUE READING
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