Variation in hydrogen peroxide sensitivity between different strains of Neisseria gonorrhoeae is dependent on factors in addition to catalase activity.

@article{Alcorn1994VariationIH,
  title={Variation in hydrogen peroxide sensitivity between different strains of Neisseria gonorrhoeae is dependent on factors in addition to catalase activity.},
  author={Timothy M. Alcorn and Hong Yi Zheng and Michael R. Gunther and Daniel J Hassett and Michael S Cohen},
  journal={Infection and immunity},
  year={1994},
  volume={62 5},
  pages={2138-40}
}
Catalase, which catalyzes the reduction of hydrogen peroxide to oxygen and water, is considered the primary defense of Neisseria gonorrhoeae against exogenous hydrogen peroxide. Recent reports have demonstrated drastically different sensitivities of the organism to hydrogen peroxide ranging from greater than 80% survival after challenge with 30 mM hydrogen peroxide to less than 0.001% survival after challenge with 10 mM hydrogen peroxide. In this study, we have examined the hydrogen peroxide… CONTINUE READING

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