Variation in acid resistance among shiga toxin-producing clones of pathogenic Escherichia coli.

@article{Large2005VariationIA,
  title={Variation in acid resistance among shiga toxin-producing clones of pathogenic Escherichia coli.},
  author={Teresa M. Large and Seth T. Walk and Thomas S. Whittam},
  journal={Applied and environmental microbiology},
  year={2005},
  volume={71 5},
  pages={2493-500}
}
Pathogenic strains of Escherichia coli, such as E. coli O157:H7, have a low infectious dose and an ability to survive in acidic foods. These bacteria have evolved at least three distinct mechanisms of acid resistance (AR), including two amino acid decarboxylase-dependent systems (arginine and glutamate) and a glucose catabolite-repressed system. We quantified the survival rates for each AR mechanism separately in clinical isolates representing three groups of Shiga toxin-producing E. coli (STEC… CONTINUE READING