Variation in Dube3a expression affects neurotransmission at the Drosophila neuromuscular junction

Abstract

Changes in UBE3A expression levels in neurons can cause neurogenetic disorders ranging from Angelman syndrome (AS) (decreased levels) to autism (increased levels). Here we investigated the effects on neuronal function of varying UBE3A levels using the Drosophila neuromuscular junction as a model for both of these neurogenetic disorders. Stimulations that… (More)
DOI: 10.1242/bio.20148045

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Cite this paper

@inproceedings{Valdez2015VariationID, title={Variation in Dube3a expression affects neurotransmission at the Drosophila neuromuscular junction}, author={Colleen Valdez and Reese S. Scroggs and Rachel Chassen and Lawrence T. Reiter}, booktitle={Biology open}, year={2015} }