Variants of the melanocyte–stimulating hormone receptor gene are associated with red hair and fair skin in humans

@article{Valverde1995VariantsOT,
  title={Variants of the melanocyte–stimulating hormone receptor gene are associated with red hair and fair skin in humans},
  author={P. Valverde and E. Healy and I. Jackson and J. Rees and A. Thody},
  journal={Nature Genetics},
  year={1995},
  volume={11},
  pages={328-330}
}
Melanin pigmentation protects the skin from the damaging effects of ultraviolet radiation (UVR). There are two types of melanin, the red phaeome-lanin and the black eumelanin, both of which are present in human skin1. Eumelanin is photoprotective whereas phaeomelanin, because of its potential to generate free radicals in response to UVR2, may contribute to UV-induced skin damage. Individuals with red hair have a predominance of phaeomelain in hair and skin and/or a reduced ability to produce… Expand
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  • F. Rouzaud, G. Costin, +7 authors V. Hearing
  • Medicine, Biology
  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2006
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Major locus for red hair color linked to MNS blood groups on chromosome 4
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