Variants of the inosine triphosphate pyrophosphatase gene are associated with reduced relapse risk following treatment for HCV genotype 2/3.

@article{Rembeck2014VariantsOT,
  title={Variants of the inosine triphosphate pyrophosphatase gene are associated with reduced relapse risk following treatment for HCV genotype 2/3.},
  author={Karolina Rembeck and Jesper Waldenstr{\"o}m and Kristoffer Hellstrand and Staffan Nilsson and Kristina Nystr{\"o}m and Anna Martner and Magnus Lindh and Gunnar Norkrans and Johan Westin and Court Pedersen and Martti F{\"a}rkkil{\"a} and Nina Langeland and Mads Rauning Buhl and Kristine M\orch and Peer Brehm Christensen and Martin Lagging},
  journal={Hepatology},
  year={2014},
  volume={59 6},
  pages={2131-9}
}
UNLABELLED The present study evaluated the impact of variations in the inosine triphosphate pyrophosphatase (ITPase) gene (ITPA) on treatment outcome in patients with hepatitis C virus (HCV) genotype 2/3 infection receiving peginterferon-α2a and lower, conventional 800 mg daily dose of ribavirin. Previous studies using higher, weight-based ribavirin dosing report that patients carrying polymorphisms encoding reduced predicted ITPase activity show decreased risk of ribavirin-induced anemia but… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 39 references

Similar Papers

Loading similar papers…