Variants of G protein-coupled receptors: a reappraisal of their role in receptor regulation.

Abstract

Truncated or shorter forms of G protein-coupled receptors (GPCRs), originating by alternative splicing, have been considered physiologically irrelevant for a rather long time. Nevertheless, it is now recognized that alternative splicing variants of GPCRs greatly increase the total number of receptor isoforms and can regulate receptor trafficking and… (More)
DOI: 10.1042/BST20150239

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