Variants in the VEGFA gene and treatment outcome after anti-VEGF treatment for neovascular age-related macular degeneration.

@article{Abedi2013VariantsIT,
  title={Variants in the VEGFA gene and treatment outcome after anti-VEGF treatment for neovascular age-related macular degeneration.},
  author={Farshad Abedi and Sanjeewa S. Wickremasinghe and Andrea Jane Richardson and Enes Makalic and Daniel F. Schmidt and Sukhpal Singh Sandhu and Paul N Baird and Robyn H. Guymer},
  journal={Ophthalmology},
  year={2013},
  volume={120 1},
  pages={
          115-21
        }
}
PURPOSE To determine the association of genetic variants of the VEGFA gene with outcome of anti-vascular endothelial growth factor (VEGF) treatment in neovascular age-related macular degeneration (AMD). DESIGN A prospective cohort study. PARTICIPANTS We included 201 consecutive patients receiving anti-VEGF injections for neovascular AMD. METHODS Patients were followed over 12 months. They were treated with 3 initial monthly ranibizumab or bevacizumab injections. Thereafter, the decision… CONTINUE READING

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