Variants in the DYX2 locus are associated with altered brain activation in reading-related brain regions in subjects with reading disability

@article{Cope2012VariantsIT,
  title={Variants in the DYX2 locus are associated with altered brain activation in reading-related brain regions in subjects with reading disability},
  author={Natalie Cope and John D. Eicher and Haiying Meng and Christopher J. Gibson and Karl Hager and Cheryl Lacadie and Robert K. Fulbright and R. Todd Constable and Grier P. Page and Jeffrey R. Gruen},
  journal={NeuroImage},
  year={2012},
  volume={63 1},
  pages={148-56}
}
Reading disability (RD) is a complex genetic disorder with unknown etiology. Genes on chromosome 6p22, including DCDC2, KIAA0319, and TTRAP, have been identified as RD associated genes. Imaging studies have shown both functional and structural differences between brains of individuals with and without RD. There are limited association studies performed between RD genes, specifically genes on 6p22, and regional brain activation during reading tasks. Using fourteen variants in DCDC2, KIAA0319… CONTINUE READING