Variants Near MC4R Are Associated With Obesity and Influence Obesity-Related Quantitative Traits in a Population of Middle-Aged People: Studies of 14,940 Danes

@article{Zobel2009VariantsNM,
  title={Variants Near MC4R Are Associated With Obesity and Influence Obesity-Related Quantitative Traits in a Population of Middle-Aged People: Studies of 14,940 Danes},
  author={Dorit P. Zobel and Camilla Helene Andreasen and Niels Grarup and Hans Eiberg and Thorkild I. A. S\orensen and Annelli Sandb{\ae}k and T Lauritzen and Knut Borch-Johnsen and Torben J\orgensen and Oluf Pedersen and Torben Hansen},
  journal={Diabetes},
  year={2009},
  volume={58},
  pages={757 - 764}
}
OBJECTIVE Variants downstream of the melanocortin-4 receptor gene (MC4R) have been reported to associate with obesity. We examined rs17782313, rs17700633, rs12970134, rs477181, rs502933, and rs4450508 near MC4R for association with obesity-related quantitative traits, obesity, and type 2 diabetes in Danish individuals. RESEARCH DESIGN AND METHODS The variants were investigated for association with obesity-related quantitative traits in 5,807 population-based sampled individuals, obesity in 14… CONTINUE READING
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