Variant type of sialyl Lewis X antigen expressed on adult T cell leukemia cells is associated with skin involvement.

@article{Furukawa1994VariantTO,
  title={Variant type of sialyl Lewis X antigen expressed on adult T cell leukemia cells is associated with skin involvement.},
  author={Yoshitaka Furukawa and Mitsutoshi Tara and Katsuyuki Ohmori and Reiji Kannagi},
  journal={Cancer research},
  year={1994},
  volume={54 24},
  pages={6533-8}
}
Expression of a variant type of sialyl Le(x) antigen defined by 2F3 monoclonal antibody on leukemia cells was studied in 15 adult T cell leukemia (ATL) patients. The expression of 2F3-defined sialyl Le(x) antigen on CD4+CD45+ cells, which is an ATL cell-rich population, was higher in patients with skin involvement (50.1 +/- 23.1% were positive) than in patients without skin involvement (18.1 +/- 12.5%) (P < 0.01). The other surface markers including classical sialyl Le(x) antigen defined by… CONTINUE READING
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