Variant on 9p21 strongly associates with coronary heart disease, but lacks association with common stroke

@article{Lemmens2009VariantO9,
  title={Variant on 9p21 strongly associates with coronary heart disease, but lacks association with common stroke},
  author={Robin Lemmens and Sh{\'e}rine Abboud and Wim Robberecht and Luc Vanhees and Massimo Pandolfo and Vincent Thijs and An Goris},
  journal={European Journal of Human Genetics},
  year={2009},
  volume={17},
  pages={1287-1293}
}
Recently, genome-wide analyses revealed that variants on chromosome 9p21 are associated with myocardial infarction. We investigated whether this association was also present in a Belgian population of coronary artery disease (CAD) patients. As CAD and ischemic cerebrovascular disease (CVD) are thought to share some pathogenic pathways, we further examined the association of 9p21 with this disease. SNP rs10757278 on chromosome 9 was genotyped in 926 patients with CAD from the CAREGENE study, in… CONTINUE READING

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