Variant of hyper-IgE syndrome: the differentiation from atopic dermatitis is important because of treatment and prognosis.

@article{Hochreutener1991VariantOH,
  title={Variant of hyper-IgE syndrome: the differentiation from atopic dermatitis is important because of treatment and prognosis.},
  author={H Hochreutener and B. W{\"u}thrich and T Huwyler and Kurt Schopfer and Reinhard Seger and K. E. Baerlocher},
  journal={Dermatologica},
  year={1991},
  volume={182 1},
  pages={7-11}
}
The hyper-IgE syndrome is characterized clinically by recurrent staphylococcal abscesses of the skin, lungs and other sites from infancy. Affected patients also have a pruritic dermatitis that differs in character and distribution from lesions of atopic dermatitis. Most lack other signs of atopic disease, develop persistent pneumatoceles and have osteopenia. Laboratory abnormalities include the consistent presence of marked hyperimmunoglobulinemia E and eosinophilia of blood, sputum and tissues… CONTINUE READING