Variant forms of the binary toxin CDT locus and tcdC gene in Clostridium difficile strains.

@article{Stare2007VariantFO,
  title={Variant forms of the binary toxin CDT locus and tcdC gene in Clostridium difficile strains.},
  author={Barbara Geric Stare and Michel Delmée and Maja Rupnik},
  journal={Journal of medical microbiology},
  year={2007},
  volume={56 Pt 3},
  pages={
          329-35
        }
}
Variability in the genes for toxin A, toxin B and other pathogenicity locus regions is well known and is the basis for the distribution of Clostridium difficile strains into variant toxinotypes. Previous data have indicated that some C. difficile strains have a non-functional truncated form of the binary toxin (CDT) locus. This study analysed variability in the CDT locus and the presence of deleted tcdC genes in C. difficile strains. A total of 146 strains were screened, including known variant… Expand

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