Variant Markers NumberCombination of HLA-B 27 , Single-nucleotide Polymorphism , and Copy Developing a Risk-scoring Model for Ankylosing Spondylitis Based on a

@inproceedings{Shim2016VariantMN,
  title={Variant Markers NumberCombination of HLA-B 27 , Single-nucleotide Polymorphism , and Copy Developing a Risk-scoring Model for Ankylosing Spondylitis Based on a},
  author={Seung-Cheol Shim and Tae-Hwan Kim and Sung-Hwan Park and Yeun-Jun Chung and Seung-Hyun Jung and Sung-Min Cho and Seon-Hee Yim and So-Hee Kim and Hyeon-Chun Park},
  year={2016}
}
Objective. To develop a genotype-based ankylosing spondylitis (AS) risk prediction model that is more sensitive and specific than HLA-B27 typing. Methods. To develop the AS genetic risk scoring (AS-GRS) model, 648 individuals (285 cases and 363 controls) were examined for 5 copy number variants (CNV), 7 single-nucleotide polymorphisms (SNP), and an HLA-B27… CONTINUE READING