Variable tidal volumes improve lung protective ventilation strategies in experimental lung injury.


RATIONALE Noisy ventilation with variable Vt may improve respiratory function in acute lung injury. OBJECTIVES To determine the impact of noisy ventilation on respiratory function and its biological effects on lung parenchyma compared with conventional protective mechanical ventilation strategies. METHODS In a porcine surfactant depletion model of lung… (More)
DOI: 10.1164/rccm.200806-975OC

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