Variable region of betanodavirus RNA2 is sufficient to determine host specificity.

@article{Ito2008VariableRO,
  title={Variable region of betanodavirus RNA2 is sufficient to determine host specificity.},
  author={Yu Ito and Yasushi Okinaka and Koh-ichiro Mori and Takuma Sugaya and Toyohiro Nishioka and Masakazu Oka and Toshihiro Nakai},
  journal={Diseases of aquatic organisms},
  year={2008},
  volume={79 3},
  pages={199-205}
}
Betanodaviruses, the causative agents of viral nervous necrosis in marine fish, have bipartite positive-sense RNA genomes. The viruses have been classified into 4 distinct types based on nucleotide sequence similarities in the variable region (the so-called T4 region) of the smaller genomic segment RNA2 (1.4 kb). Betanodaviruses have marked host specificity, although the primary structures of the viral RNAs and encoded proteins are similar among the viruses. We have previously demonstrated… CONTINUE READING

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