Variable morphological differentiation of a raphé-derived neuronal cell line following transplantation into the adult rat CNS.

@article{Onifer1993VariableMD,
  title={Variable morphological differentiation of a raph{\'e}-derived neuronal cell line following transplantation into the adult rat CNS.},
  author={Stephen M. Onifer and Scott R Whittemore and Vicky R. Holets},
  journal={Experimental neurology},
  year={1993},
  volume={122 1},
  pages={130-42}
}
A clonal, neuronally-differentiating cell line, RN33B, was previously developed by retroviral infection of neural tissue derived from embryonic Sprague-Dawley raphé nuclei with a retrovirus encoding the temperature-sensitive allele of SV40 large T-antigen. In the present study, RN33B cells were transplanted into two target areas of the raphé nuclei, the… CONTINUE READING